Selected Publications

Pignatelli M, Tejeda HA, Barker DJ, Bontempi L, Wu J, Lopez A, Palma Ribeiro S, Lucantonio F, Parise EM, Torres-Berrio A, Alvarez-Bagnarol Y, Marino RAM, Cai ZL, Xue M, Morales M, Tamminga CA, Nestler EJ, Bonci A. Cooperative synaptic and intrinsic plasticity in a disynaptic limbic circuit drive stress-induced anhedonia and passive coping in mice. Mol Psychiatry. 2020 doi: 10.1038/s41380-020-0686-8. PubMed PMID: 32161361.

Pignatelli M, Bonci A. Spiraling Connectivity of NAc-VTA Circuitry. Neuron. 2018 Jan 17;97(2):261-262. PubMed PMID: 29346748.

Pignatelli M, Umanah GK, Ribeiro SP, Chen R, Karuppagounder SS, Yau HJ, Eacker S, Dawson VL, Dawson TM, Bonci A. Synaptic Plasticity onto Dopamine Neurons Shapes Fear Learning. Neuron. 2017 Jan 18;93(2):425-440. PubMed PMID: 28103482

Umanah GKE, Pignatelli M, Yin X, Chen R, Crawford J, Neifert S, Scarffe L, Behensky AA, Guiberson N, Chang M, Ma E, Wan Kim J, Castro CC, Mao X, Chen L, Andrabi SA, Pletnikov MV, Pulver AE, Avramopoulos D, Bonci A, Valle D, Dawson TM, Dawson VL. Thorase variants cause defects in glutamatergic signaling and behavioral deficits: rescue by Perampanel. Science Transl Medicine. 2017 Dec 13;9(420). PubMed PMID: 29237760

Edwards NJ, Tejeda HA, Pignatelli M, Zhang S, McDevitt RA, Wu J, Bass CE, Bettler B, Morales M, Bonci A. Circuit specificity in the inhibitory architecture of the VTA regulates cocaine-induced behavior. Nat Neurosci. 2017 Mar;20(3):438-448. PubMed PMID: 28114294

Tejeda HA, Wu J, Kornspun AR, Pignatelli M, Kashtelyan V, Krashes MJ, Lowell BB, Carlezon WA Jr, Bonci A. Pathway- and Cell-Specific Kappa-Opioid Receptor Modulation of Excitation-Inhibition Balance Differentially Gates D1 and D2 Accumbens Neuron Activity. Neuron. 2017 Jan 4;93(1):147-163. doi: 10.1016/j.neuron.2016.12.005. PubMed PMID: 28056342

Pignatelli M, Bonci A. Role of Dopamine Neurons in Reward and Aversion: A Synaptic Plasticity Perspective. Neuron. 2015 Jun 3;86(5):1145-57. Review. PubMed PMID: 26050034